Are you a newcomer to Destiny 2, unsure of which hand cannons to use in PvE? Look no further! We have ranked all the best hand cannons in Destiny 2, providing you with the top choices based on their effectiveness in battle. Say goodbye to the frustration of trial and error and hello to making the most of every battle.
Hand cannons are one of the most iconic weapon types in Destiny 2, offering high damage and precision at close to medium range. In PvE, hand cannons can be incredibly effective against a variety of enemies, from low-level trash mobs to high-level bosses.
However, not all hand cannons are created equal, and some are simply better than others. In this article, we’ll be taking a look at the best hand cannons for PvE in Destiny 2 and ranking them based on their effectiveness in a tier list.
Keep in mind that this Destiny 2 tier list is based on the latest expansion, Lightfall, so be sure to take that into account when making your selection. Get ready to dominate the battlefield with the perfect weapon in your hands!
Also, to play with the best PvE classes, check out our Destiny 2 class tier list.
We have updated our Best PvE Hand Cannons in Destiny 2 tier list on April 14, 2023
S-Tier – Best Hand Cannons in Destiny 2 PVE
Hand cannons in the S-tier are the absolute best guns for PvE content. They offer high damage, impressive range, and powerful perks that make them incredibly versatile and effective in a variety of situations.
These hand cannons are top-tier choices for players who want to quickly eliminate enemies and take down bosses with ease:
- Zaouli’s Bane
- Ace of Spades
- Eriana’s Vow
Even though all of these hand cannons are OP in current D2 PVE Meta, my favorite still is Ace of Spades. This Exotic hand cannon remains a top choice for PvE players, thanks to its combination of high damage, precision, and utility.
Its signature Firefly perk can cause enemies to explode on precision kills, making it great for clearing out groups of enemies, and its Memento Mori perk grants bonus damage after a kill, allowing it to deal massive damage to bosses.
Related: Best Bloodborne Weapons
A-Tier – Destiny 2 Weapons
Hand cannons in the A-tier are still excellent choices for PvE, with high damage and versatile perks that make them effective against most enemies.
While they may not be quite as powerful as S-tier hand cannons, they are still highly effective and reliable and can be a great choice for players who prefer a particular playstyle or weapon type:
- Nation of Beasts
- Midnight Coup
From this list Nation of Beasts stands out on top for me. This Legendary hand cannon is a favorite of many PvE players, thanks to its high damage, fast fire rate, and Dragonfly perk, which causes enemies to explode on precision kills.
It’s a solid all-around hand cannon that can quickly eliminate most enemies, and its Rampage perk grants bonus damage after a kill, making it even more effective.
The Sunshot hand cannon also has a lot of potential, thanks to its fast fire rate and ability to chain explosions on kills. However, it suffers from low damage and a small magazine size, making it less effective against tougher enemies.
Trust is a Legendary hand cannon that is a great choice for players who prefer a more forgiving playstyle, thanks to its fast fire rate, high stability, and Explosive Payload perk, which deals additional damage on impact. It’s not as OP as the most powerful hand cannons from tier S, but it’s reliable and effective in most situations.
Related: Splatoon 3 Weapon Tier List
B-Tier – Destiny 2 Weapons
Hand cannons in the B-tier are solid choices for PvE, with reliable damage and perks that make them effective in most situations.
They may not be the most powerful or versatile hand cannons, but they are still highly effective and can be a great choice for players who prefer a more forgiving play style:
- The Palindrome (Adept)
- Something New
- Ancient Gospel
- Jack Queen King 3
Related content: Monster Hunter Rise Best Weapons
C-Tier Hand Cannons
Hand cannons in the C-tier are the least effective choices for PvE. While they may still be fun to use in low-level content, they are generally not reliable or effective against tougher enemies or in high-level content.
These hand cannons may have some redeeming qualities, but they are generally not recommended for serious PvE players:
- True Prophecy
- Igneous Hammer
- The Last Word
- Crisis Inverted
Related: CSGO Weapon Tier List
Hand cannons are a popular weapon type in Destiny 2, and they can be highly effective in PvE content. However, not all hand cannons are created equal, and some are much more effective than others. By using this tier list, players can quickly identify the best hand cannons for their playstyle and the content they want to tackle.
We hope you found our Best Hand Cannons in Destiny 2 tier list helpful! If you have any thoughts or feedback on our rankings, please share them with us in the comments section below. Remember, this is just our opinion based on our experience with the game and our research. Everyone’s opinion can vary, and that’s what makes the game exciting!
Our main goal with this guide is to provide you with an overview of the best hand cannons for PVE in Destiny 2, so that you can make an informed decision when choosing your weapon. We’ve put together a well-balanced list to assist you, but feel free to follow or ignore our advice – after all, the choice is ultimately yours and depends on your playstyle.
Which one is your favorite hand cannon for PvE? I’m Thorn between Ace of Spades (Miss my bro Cayde-6) and Nation of Beasts.
Frequently Asked Questions
Hand cannons that are good for PvE generally have high damage, good range, and useful perks that make them effective against a wide range of enemies.
Yes, many of the hand cannons on this list are highly effective in endgame content like raids and Nightfall strikes.
Yes, all of the hand cannons on this list are currently available in Destiny 2. Some may be easier to obtain than others, but all are obtainable through various activities in the game.
No, while the hand cannons on this list are highly effective, there are other hand cannons and other types of guns in the game that may be just as effective for your play style. Use this list as a guide, but don’t be afraid to experiment with other weapons as well.
Yes, as Destiny 2 updates and new weapons are added to the game, this tier list may change. Be sure to check back regularly for updates and changes to the list.
Don’t forget to rate our Best Destiny 2 PVE Hand Cannons Tier List below!